'pioneering'
[pioneer.v.01] as in: open up an area or prepare a way


Examples:
She pioneered a graduate program for women students



'pioneering'
[initiate.v.02] as in: take the lead or initiative in; participate in the development of


Examples:
This South African surgeon pioneered heart transplants



'pioneering'
[pioneer.v.03] as in: open up and explore a new area


Examples:
pioneer space


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