Words with a similar base: derangement

'derangement'
[derangement.n.01] as in: a state of mental disturbance and disorientation


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'derangement'
[upset.n.02] as in: the act of disturbing the mind or body

Examples:
his carelessness could have caused an ecological upset
she was unprepared for this sudden overthrow of their normal way of living


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